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Aptar Pharma’s Airless+ semi-solid dispensing systems offer safe and reliable metered dispensing of several skin medication types while protecting them from exposure to air. The Airless+ system is ideal for protecting gel, cream and lotion products as well as providing clean and precise skin treatment dosing of different viscosities. Our Airless+ systems come with actuator, container size and dose volume options, that deliver consumer convenience and brand differentiation.

 

The Airless+ Advantage for Skin Medication Dispensing

Aptar Pharma’s Airless+ dispensing systems were designed with product protection in mind. No air can enter the dispensing system throughout the life of the product, thus protecting even the most sensitive formulations. As the semi-solid skin treatment is dispensed from the metered pump system, the displaced product volume is not replaced with external air. Instead, the physical movement of a piston compensates for the evacuated formulation, leaving no unoccupied headspace. Airless+ dispensing systems protect their contents from air and light for enhanced product shelf life.

Woman athlete in black clothes seated on green grass dispenses white cream from Apar Pharma Airless+ dispenser on leg.

Airless+ Delivery Advantages For Skin Conditions

Offering clean, precise dispensing in a portable, easy to use format makes Airless+ dispensers ideal for patients with a range of skin conditions. Airless+ dispensers are also easy to integrate onto standard filling lines and can provide product differentiation opportunities for pharmaceutical companies.

Skin Medication Formulation Flexibility

Airless+ dispensing systems accurately dispense gels, creams, and lotions in a wide range of viscosities.

Woman with long dark hair wearing grey suit jacket dispenses dermal product on hand from white Aptar Airless+ delivery system

Airless+ Protection for Semi-Solid Formulations

Aptar Pharma’s Airless+ dispensing systems provide clean and hygienic product application with optional protective features designed to keep air away from valuable semi-solid skin formulations.

Airless+ Dispensing of Skin Treatment for a Range of Conditions

Our Airless+ system is ideal for dispensing treatments for chronic or acute skin conditions including acne, atopic dermatitis, eczema, minor burns, psoriasis, rosacea, topical analgesics, transdermal hormones and wound care.

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Airless+ Delivery Advantages for Skin Conditions

There are numerous benefits for the pharmaceutical product company that chooses the Airless+ system. The reliable dispensing system protects the skin treatment product from damage caused by both light and air throughout the product’s lifecycle. It offers precise dispensing, minimal waste of valuable product, and the emptied dispensing system is more easily recycled by the consumer. With a variety of different actuators, Airless+ systems can provide pharmaceutical companies with both product and brand differentiation in the competitive skin treatment market. Aptar Pharma offers both Top- and Bottom Fill models of its Airless+ systems that can easily integrate onto most standard filling lines. Our experienced technical experts provide on-site and remote support to streamline the implementation of Airless+ dispensers on customer filling lines.

The Airless+ system provides numerous benefits for consumers as well. For those with chronic or acute skin conditions, the dermal dispensing system’s intuitive handling and ease of use contribute to greater patient compliance as well as a positive user experience. Our Airless+ dispensing systems provide clean and hygienic dispensing, in combination with reliable and precise dosing of skin medications. Airless+ systems come in sizes that are portable and discrete for a more convenient on-the-go skin treatment option. Available with Child-Resistant Senior-Friendly (CRSF) safety features, Airless+ dispensing systems are designed to prevent unintended access by children while easy and intuitive to handle for seniors. Aptar Pharma’s Airless+ systems provide reliable dispensing of cream, lotion, or gel formulations to the skin from virtually any position making administration easy for patients.

Aptar Pharma Airless+ systems schematic showing range of container sizes, actuators and dose volumes.

Skin Condition Formulation Flexibility

Today’s treatments applied via the skin can come in a variety of formats. However, many are formulated as semi-solids including gels, creams, or lotions in a variety of viscosities that need to be precisely dispensed. Aptar Pharma’s Airless+ dispensing system is flexible enough to be able to reliably dispense such formulations, while providing enhanced protection from external light and air. With container sizes of 5 to 100 ml and dosing volumes of 200 to 1000 µl, Airless+ systems provide a wide range of dispensing capabilities. Further customization can be achieved through Aptar Pharma’s range of available actuators.

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Airless+ Protection for Semi-Solid Formulations

Aptar Pharma’s Airless+ dispensing systems provide semi-solid gel, cream, or lotion formulations with protection from light and air. Suitable for even the most sensitive skin or dermal treatments, Airless+ dispensing pump systems combine product protection with clean and hygienic operation. Our Airless+ dispensing systems use their metered pump system with a variety of actuators to deliver precise dosing for a diverse range of skin condition treaments. With the Airless+ system, the product is not replaced with external air within the Airless+ system. Instead, the physical movement of the piston compensates for the evacuated formulation, avoiding headspace and thereby protecting the sensitive product. Our Airless+ systems are made of 100% medical grade resins and meet the highest quality and regulatory standards.

Woman with long brown hair seated in chair dispenses dermal cream on elbow from Aptar Airless+ drug delivery system

Airless+ Dispensing of Skin Treatment for Range of Conditions

Aptar Pharma’s Airless+ dispensing pump systems were designed to dispense precise doses of semi-solid skin formulations for a range of conditions. The Airless+ system can prove an ideal delivery system for many of today’s chronic or acute skin conditions including:

  • Acne
  • Atopic dermatitis
  • Eczema
  • Itching
  • Minor burn treatments
  • Psoriasis
  • Rosacea
  • Topical analgesics
  • Transdermal hormones
  • Wound care

With such a variety of applications, the Airless+ system is flexible and robust enough to meet the requirements of a variety of critical skin treatments. Aptar Pharma brings the experience that can make your next treatment for skin conditions a success. Our Airless+ systems are used to dispense over 50 prescription dermal products launched in regulated markets worldwide.

Aptar Pharma Airless+ Top Fill Options

Airless+ dermal dispensing pump systems can be run on most common industry standard filling lines. Our Airless+ Top Fill models are suitable for a wide range of viscosities and come in many configurations supporting product requirements and brand differentiation needs. Individual piston pre-positioning is an available option for added convenience and efficiency. Our Airless+ systems benefit pharmaceutical companies by supporting precise filling, enabling faster priming and minimizing residual drug waste.

Here are our Airless+ Top Fill models:

  • Mezzo+
  • Micro+
  • Nano+
  • NanoCR+

Aptar Pharma Airless+ Bottom Fill Options

Our Airless+ Bottom Fill model is designed to accommodate even the highest viscosity semi-solid formulations. Bottom Fill models integrate easily onto most standard filling lines and offer easy to adjust fill volumes. Aptar Pharma’s Airless+ dermal dispensing systems come in a broad range of configurations, meeting the requirements of even the most demanding formulations for skin treatment applications.

Her are our Airless+ Bottom Fill models:

  • MiniCR+

White Airless+ dispenser surrounded by 6 blue circles representing Aptar support services.

Airless+ Dispensing System Technical Support

Aptar Pharma offers comprehensive on-site and remote filling support for its complete range of Airless+ dispensing systems. With technical filling support and applicable regulatory documentation available, Aptar Pharma makes Airless+ dispensing systems the easy choice for today’s skin treatment products.

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Airless+ – For More Sustainable Skin Treatment Solutions

Aptar Pharma’s Futurity™ brand encompasses the many strategic solutions that we deploy towards our goal of achieving enhanced sustainability, including initiatives such as improved recyclability, reduced CO2 footprint, the use of alternative materials and refill/reload/reuse designs. Our Airless+ dispensing systems are prime examples of our commitment to providing greater sustainability through our products. The Airless+ range of skin treatment dispensing systems are made entirely of plastics and are free of recycling disruptors such as metals, earning them a 97%-98% recyclability rating from cyclos-HTP. Manufactured at International Sustainability & Carbon Certification (ISCC) PLUS certified sites, Aptar Pharma has implement a mass balance accounting system that traces the use of more sustainable materials, such as chemically recycled resins, bio-circular or renewable feedstocks, throughout the chain of custody for each Airless+ product.

In addition, the Airless+ system’s piston technology results in highly efficient product dispensing that minimizes the amount of formulation waste left in the dispenser, making them ideal for direct recycling by consumers in existing recycling pathways. Our Micro+  Futurity™ Airless system takes recyclability a step further through its monomaterial design, composed of only medical grade polyethylene (PE) resin, which results in a higher quality of recyclate. The Micro+ Futurity™ Airless system has achieved cyclos-HTP’s highest recyclability rating of “Class AAA+” which is 100% recyclable. All of our Airless+ systems protect even the most sensitive formulations from air or environmental influences while providing precise and efficient dispensing of today’s skin treatment products.

Learn more about Aptar Pharma’s broader commitment to sustainability through its Futurity™ platform

Details on Aptar Pharma’s Airless+ Skin Medication Dispensing Range and Extended Support

 

Our Airless+ skin medication dispensing range includes a variety of delivery systems composed of only medical grade resins suitable for pharmaceutical use. With numerous functional component combinations and the individual piston pre-positioning service performed by Aptar Pharma, we can supply the widest range of Airless+ devices. Our flexible Airless+ dispensing systems provide dosing options ranging from 200 µl to 1000 µl combined with container size options ranging from 5 ml to 100 ml. Airless+ skin medication dispensing systems provide brand differentiation and numerous available actuator designs. Our self-closing actuators excel at product protection and preventing the dermal formulation from drying or clogging. Aptar Pharma’s Airless+ range includes both Top- and Bottom Fill models that can seamlessly be introduced to most standard filling lines.

Our innovative Child-Resistant Senior-Friendly (CRSF) solutions prevent accidental product access by children, while being intuitive and easy-to-use for seniors. Our certified child-protection features have become increasingly important in the growing topical pain treatment, medical cannabis/CBD, and rosacea care segments, where products are delivered by skin application.

Aptar Pharma’s regulatory experts stay up to date with current pharma regulations including those for drug-device combination products. We can offer comprehensive Drug Master File (DMF) support and data on the Airless+ system’s well-characterized medical grade resins for applicable U.S. and Chinese market applications. Aptar Pharma’s Airless+ Extended Support (ES) provides pharmaceutical companies with applicable test reports, in submission ready formats. Our drug-device combination product support packages include relevant device documentation meeting 21 CFR 820.30 (US) and MDR 2017/745, GSPR (EU) drug-device combination requirements.

Partner with Aptar Pharma for your Skin Disease Treatment with Airless+ Dispensing Systems

Our Airless+ dispensing systems provide enhanced product protection from light and air contributing to a stable shelf life. The benefits of Aptar Pharma’s Airless+ dispensing technology on treatments designed for skin application can be significant for pharmaceutical companies and patients alike. Let Aptar Pharma’s experts take you from formulation to patient while reducing development risks and increasing speed-to-market for your next skin condition treatment.

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