Prohaler® Multi-dose Dry Powder Inhaler

Inhalers, Dry Powder Inhalers
Pharmaceutical, Inhalation

Prohaler® is a high performance, multi-dose dry powder inhaler (DPI) that helps to improve patient compliance and adherence in the treatment of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). It is activated by simply breathing. It’s lightweight and intuitive design is easy to use and suitable for all patient types.

Aptar Pharma ProHaler® multidose dry powder inhaler (DPI) with transparent cover and body showing blue internal parts.
Aptar Pharma ProHaler® multidose dry powder inhaler (DPI) with transparent cover and body showing blue internal parts.
The Aptar Pharma ProHaler® multidose dry powder inhaler (DPI) with closed blue cover on white background.
The Aptar Pharma ProHaler® multidose dry powder inhaler (DPI) with open blue cover on white background.

A Multi-Dose DPI for Improved Patient Compliance

 

Woman with dark hair wearing blue sweater in her house is holding blue Aptar Pharma ProHaler® Inhaler solution to her mouth. Woman with dark hair wearing blue sweater in her house is holding blue Aptar Pharma ProHaler® Inhaler solution to her mouth. Woman with dark hair wearing blue sweater in her house is holding blue Aptar Pharma ProHaler® Inhaler solution to her mouth. Woman with dark hair wearing blue sweater in her house is holding blue Aptar Pharma ProHaler® Inhaler solution to her mouth.

  • Innovation in Dry Powder Inhalation

    Dry powder inhalers are activated by breathing and we developed a high performance, multi-dose dry powder inhaler (DPI) device by focusing on simplicity of use for improved patient compliance.

  • Patient Focused Features

    Our proprietary Prohaler® multi-dose inhaler has several features that can improve patient compliance and ease of use. The device is portable and compact and no coordination is needed. With powder formulation efficiency measures and a visual dose counter with audible click sound indicator, patients can be confident of successful dose delivery.

  • Clinic and Patient Ready

    The Prohaler® DPI is a proven solution for multi-dose dry powder inhalation.  This technology has molding and assembly capabilities in place that are capable of supporting your needs so that Aptar Pharma can help to accelerate and de-risk your Dry Powder Inhaler (DPI) programs.

  • Integrated Support & Development Services

    Our extensive inhalation development support services include DPI device selection, formulation development, analytical method development and validation as well as comprehensive regulatory support.

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Close up of patient in blue sweater with light colored hair inspecting a green ProHaler inhalation solution with covers open.

Innovation in Dry Powder Inhalation

We understand the challenges that asthma and COPD patients face in managing their conditions and maintaining compliance with their treatment regimens. When our dedicated teams of inhalation R&D scientists worked with international thought leaders and patients, their goal was to design and deliver a simple, reliable and intuitive multi-dose dry powder inhaler (DPI) system that would enhance patient compliance and adherence.

We made the device lightweight and portable so that it’s really easy to use. Dose indication and acknowledgement are an integrated part of the design to provide patients with confidence to self-manage their treatment. We designed Prohaler® using the QbD (Quality by Design) approach and this allowed us to ensure that the product meets the desired performance standards, is safe and reliable, and is easy to use by patients. Additionally, the use of QbD enabled us to minimize the risk of product failure and maximize the likelihood of success.

With only three simple steps to operate: Open, Breathe-in, Close (OBIC) practically all patients can use Prohaler®.

Close up of man in dark shirt holding green Aptar Pharma ProHaler multidose dry powder inhaler to mouth for administration.

Patient focused features

Prohaler® is lightweight and portable and intuitive to use so it can always stay with the patient. It carries up to 30 individual powder doses in separate sealed laminated blisters for optimal moisture protection.

With an integrated visual dose indicator, the user knows if there are doses remaining in the device. Prohaler® also incorporates an audible click noise when the dry powder dose is administered so the user can easily confirm dosing success.

With its unique breath-triggered blister opening mechanism, Prohaler® reduces dose wastage, which can be a common problem with other conventional DPIs.

Gloved hands operating a computer running specialized analytical testing on Aptar DPI solution based product attached to stand.

Integrated Support & Development Services

We are a trusted authority and leading company for the latest innovations in inhalation and dry powder inhaled drug delivery. This is based on our decades long experience in this specialized drug delivery route. Aptar Pharma offers comprehensive development and support services to help our customers derisk and accelerate the process of bringing these important respiratory products to the patients that need them most.

Our extensive knowledge of dry powder inhalation products, our broad range of specialized formulation development, analytical development, technical and regulatory support can help guide customers through the challenging and constantly evolving regulatory approval landscape.  Aptar Pharma is your ideal partner for new or repositioned multi-dose DPI products.

Advantages of Prohaler® Dry Powder Inhaler

 

  • Easy to use

  • Convenient to carry

  • Breath-triggered dose opening

  • Assured dose delivery

  • For a wide range of patient types

  • Powerful dose dispersion

  • Optimal moisture protection

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    Prohaler® is simple and intuitive to use, even for emergency use

    Simply Open, Breath-in and Close (OBIC) are the three steps required for DPI dosing. Suitable to reliably treat acute or chronic symptoms with no requirement for complicated instructions or complex preparation steps.

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    Our Prohaler® is small and lightweight

    Easily and conveniently portable in a purse, pocket, or bag.

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    Our Prohaler® has unique breath-triggered blister opening

    This elevates powder protection and avoids wasted dosages seen with other common DPI technologies.

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    See and hear dosage delivery with Prohaler® indicators

    A visual dose counter and audible click provide patients with reassurance of successful dry powder dose delivery every time.

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    Consistent performance for a broad range of patients

    The Prohaler® design ensures the application of an optimized, consistent inspiratory flow, minimizing the impact of patient-to-patient variability.

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    Our Prohaler has a powerful dose dispersion engine for consistent performance

    Highly effective powder de-agglomeration and dispersion safeguards successful dose delivery.

  • Woman with brown hair in a beige shirt sitting on grey sofa raises a green and grey Prohaler solution to her mouth.

    Our Prohaler® holds 30 blister sealed powder doses

    For optimal moisture protection all 30 individual dry powder doses are sealed in sealed foil laminated blisters maximizing shelf life and product performance.

Let Us Help you Find the Optimal Respiratory Solution for Patient Compliance.

Contact us now and benefit from our proven know-how in innovative inhalation solutions.

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