Aptar pharma logo

At Aptar Pharma, we understand your challenges in dermal drug delivery and turn them into opportunities for you.

We offer a broad range of versatile dispensing solutions, leveraging our human factor and digital healthcare capabilities, to strengthen your brand presence.

We provide expertise in regulatory support and technical guidance to accelerate and derisk your path to market while ensuring product quality, compliance and sustainability.

Aptar Pharma is more than just a supplier - we are your preferred drug delivery partner for developing your dermal combination products all the way from formulation to patient.

Your Partner in Dermal Drug Delivery Solutions

 

With decades of experience in the design and manufacture of a portfolio of dermal drug delivery systems, Aptar Pharma offers products with a unique combination of dermal dispensing features backed with extensive regulatory and technical expertise that can accelerate and derisk the development of drug device combination products.

Applying medication to the skin can require precise and reliable dosing from a dispensing system that also protects the liquid, gel, cream or lotion formulation from external contamination or conditions.

From topical applications applied directly to the skin or dermal systemic indications, dermal drug delivery can offer numerous advantages through the use of Aptar Pharma’s advanced dermal drug delivery systems and support services.

Range of dermal drug delivery systems including spray pumps, airless dispensers, and child-resistant packaging formats for different applications.

Flexibility to Dermal Drug Markets

 

We provide the flexibility you need to support and widen your dermal drug delivery product portfolio.

With an extensive history of success in the dermal segment, Aptar Pharma truly understands the needs of dermal drug manufacturers and product users from markets with varying levels of regulation.

Our broad portfolio of dermal drug delivery solutions can meet the varying requirements of a range of formulations, products and patient needs.

Aptar Pharma can also provide custom solutions for your next innovative product covering prescription innovator, OTC consumer or generic product applications.

User applying a dermal formulation using a spray pump onto the elbow, illustrating delivery of liquid or semi-solid formulations to the skin.

Range of Dermal Formulation Types

 

Our portfolio of dermal drug dispensing solutions can support a broad range of galenic forms, including liquid and semi-solid formulations for dermal and topical applications.

  • Airless+ systems can dispense formulations covering a wide range of viscosities, from lotions to creams, in a sealed system protected from light and air.
  • Spray Pumps represented by APFPlus, Classic Line and VP6 pump technologies can deliver formulations with a range of viscosities to the skin.
  • Bag-On-Valve (BOV) is compatible with a broad range of liquid to semi-solid formulations including gels and creams.

User applying a dermal formulation to the knee using an airless dispensing system for targeted topical or transdermal application.

Growing Therapeutic Dermal Applications

 

Aptar Pharma manufactures and supplies a portfolio of dermal drug delivery technologies that are suitable for a range of therapeutic applications.

From topical skin treatments to transdermal pain relief, advanced wound care or hormone treatments, Aptar Pharma’s dermal drug delivery technologies have been widely used in many different dermal drug applications.

Technical illustration of a spray pump with tip seal mechanism showing closed and open positions to prevent contamination through the orifice.

Hygienic Dermal Product Protection

 

Our dermal drug delivery systems offer clean and hygienic dispensing combined with robust product protection.

  • Airless+ semi-solid dispensing systems protect sensitive formulations from air and light.
  • Aptar’s BOV system separates the formulation from the propellant thanks to its multi-layer bag, providing a high level of barrier protection against diffusion while helping protect sensitive formulations.
  • APFPlus Top Seal technology uses a spring-loaded mechanism to close the spray orifice after each actuation, helping to protect preservative-free formulations from contamination and prevent nozzle clogging.

The illustration of the dermal dispensing spray pump with 360-degree functionality

Innovative Dermal Dispensing

 

Aptar Pharma has developed high-quality and innovative dermal drug delivery systems that can be customized to individual needs.

For some solutions, customized options such as color, printing, and more are available to help you support your unique brand presence.

Collage of dermal application areas including face, shoulder, and hands, illustrating different types of topical and dermal treatment uses.

Versatile Solutions for Dermal Formulations

 

Aptar Pharma’s dermal drug delivery solutions are designed to meet the performance requirements demanded by a range of today’s formulation viscosities, galenic forms or device technologies.

Our portfolio of dermal delivery systems can dispense a wide range of formulation viscosities, supporting the requirements of most applications.

Dermal Product & Drug Delivery Technology Features

Aptar Pharma offers dermal drug delivery solutions that help to advance your journey to market.

We offer specialized dermal drug device combination product development services, supported by manufacturing, regulatory and custom design capabilities.

User dispensing a measured amount of dermal formulation from spray pumps and Airless+ technologies into the hand.

Clean & Hygienic Dermal Dispensing

Our dermal spray pump and Airless + technologies provide precise metered dispensing of liquid to semi-solid formulations in a clean and hygienic format.

User applying dermal formulation with a portable spray pump directly onto the shoulder for convenient use.

Convenient Dermal Delivery

Aptar Pharma’s dermal drug delivery solutions, such as the Airless + and BOV systems, offer intuitive, reliable, and portable designs for ease-of-use and flexibility. With 360-degree spray pump actuation or 360-degree Airless + dispensing, our dermal delivery systems can be conveniently used virtually anywhere in any position.

User opening a dermal dispensing container with a protective cap designed to prevent contamination and unintended access.

Dermal Product Protection

Aptar Pharma’s dermal drug delivery solutions are designed to minimize exposure to air, light, moisture or, in case of our preservative-free solutions, of bacteria ingress. Our Airless + and BOV system focus on protecting the product from contact with air and light. Child Resistant – Senior Friendly (CRSF) features are available on selected systems to help prevent unintentional use.

User dispensing a controlled amount of dermal formulation from a metered pump onto the hand for precise application.

Precision Dermal Dosing

Aptar dermal delivery solutions, such as advanced metered pumps, are designed to deliver consistent and precise doses of semi-solids (gels, creams, lotions) and liquid formulations across a range of viscosities with limited formulation waste. Aptar dermal delivery systems offering high-evacuation rates help to deliver consistent dosing to the end of the product’s use.

User applying dermal formulation from a recyclable Airless+ spray pump designed for sustainable dispensing.

Sustainable Dermal Dispensing

Aptar Pharma’s Futurity® products integrate eco‑design principles as part of a lifecycle‑based development approach, focusing on recyclability, circularity considerations, and carbon‑impact trade‑off assessments.

 

Aptar Pharma´s Airless + systems are certified for their recyclability performance, and Micro +   Futurity® in particular has achieved a ‘’Class AAA+’’ from Cyclos‑HTP* recyclability rating due to its monomaterial design. Aptar Pharma produces its Airless + systems in an ISCC Plus certified site with the option to leverage the mass balance approach, enabling the use of renewable feedstocks and therefore reducing the use of conventional fossil-based plastics.

*Valid for Germany and Netherlands

Dermal Product Patients & Consumers

Aptar Pharma has developed dermal drug delivery systems with the patient or consumer in mind.

By truly understanding the impact of our products on the user, we are able to define the performance parameters and usability standards for dermal drug delivery products and deliver an advanced patient- and user experience.

Digital interface displaying regulatory and compliance icons including FDA, documentation, and quality systems.
Digital interface displaying regulatory and compliance icons including FDA, documentation, and quality systems.

Dermal Product Regulatory Support

Aptar Pharma offers comprehensive regulatory support for its delivery device components and maintains Drug Master Files (DMFs) for Airless + and Classic Line dermal delivery solutions. Our regulatory experts continuously monitor evolving regulations worldwide to help minimize compliance issues that could lead to regulatory delays or rejections, supporting smoother ANDA, NDA, and international submission processes.

Our objective is to help accelerate your market access by supporting compliance, audit and inspection readiness through robust documentation and quality systems. We are experienced in supporting multi-regional product launches, offering market-tailored documentation, human- factors data, and risk management inputs, to support efficient approval processes across geographic markets.

Pharmaceutical experts collaborating in a meeting to review dermal drug delivery device development, analysis, and technical support strategies.

Technical Support Services

Aptar Pharma’s comprehensive development and technical support help customers to accelerate the journey from pre-clinical, to clinical and ultimately to market.

Our expert device analysis and material compatibility testing aid in efficient device selection. We leverage our well-established platforms and deep technical expertise to arrive at a well-documented, robust dermal delivery solution. Hence, those solutions consider key regulatory expectations, including those of the U.S. FDA and EMA, to support your finished‑product dossier.  

Our proactive risk management strategies are intended to mitigate compliance issues, build trust and support sustained performance throughout the product’s market life.

Noble researchers performing Human Factors testing on a dermal applicator device.

Human Factor Studies

Noble , an Aptar Pharma company is an industry leader in patient onboarding, drug delivery training, and human factors studies. Through integrated Human Factors Engineering (HFE) and hands-on testing, we generate data-driven insights to inform design decisions, reduce user errors, support regulatory approval with global health authorities, and drive market differentiation. This expertise improves usability, patient adherence, safety, and overall satisfaction, while accelerating development timelines and commercialization.

User interacting with a digital health app on a smartphone to manage symptoms and treatment adherence.

Digital Health Solutions

Aptar Digital Health division, Aptar Pharma offers digital health solutions to enhance user experience and patient adherence. Leveraging advanced capabilities in connected hardware and software development, we build products and services to empower patients with chronic disease and build relevant insights around their experience and their journey towards better health. Aptar Pharma supports the development of digital technologies for both non-regulated and regulated products. We support our partners in building digital solutions for faster clinical validation, improved treatment outcomes, and product differentiation in the dermal drug delivery market.

We Have a Broad Range of Value Added Services to Accelerate and Derisk Your Drug Product Development.

Start a Project With Us

We Thrive on Transforming Ideas into Opportunities – Let Yours be Next.

Dermal Product Solutions

Our comprehensive range of advanced dermal drug delivery technology solutions can provide precise, reliable and patient-friendly dosing of dermal liquids and semi-solids (gels, creams, lotions, ointments) to meet the global requirements of patients and drug manufacturers.

Find the right solution for your dermal drug delivery product or contact Aptar Pharma today.

Company

Legal

© 2026 Aptar.com. All rights reserved.