Intranasal Immunization: Promises and Challenges

Today, there are just three marketed intranasal vaccines available for human use but many more are in development for both human and veterinary applications. This webinar provides an overview of intranasal vaccine formulation for liquid and powder administration. The pros and cons of intranasal vaccines are discussed and appropriate technology platforms are examined. There is also discussion of the logistical considerations that need to be taken into account and the opportunities that intranasal vaccination can offer. Nasal vaccination provides a convenient, easy to administer alternative to injection that can trigger mucosal immunity via interaction with immune modulators present in the nasal cavity. The nasal associated lymphoid tissue (NALT) region plays a dominant role in this mechanism and is consequently often a prime target for nasal spray vaccines.