Drug Repositioning – Benefits and Challenges for Lifecycle Management

The webinar also highlights the growing trend of reformulating drugs for nasal delivery. This method is gaining popularity due to its ability to empower patients by reducing their dependence on HCPs. Nasal drug delivery, allowing for direct access to systemic circulation, has proven especially beneficial for emergency treatments. An example presented is the reformulation of naloxone, used for treating opioid overdoses, demonstrating the efficacy of nasal drug products in critical situations.

However, the process of nasal drug repositioning is not without challenges. The webinar discusses various scientific and regulatory obstacles that must be navigated. Important considerations include determining appropriate dose levels and regimens, as well as ensuring therapeutic efficacy across new patient populations. These factors underscore the complexity involved in successfully repositioning a drug for nasal administration.

The webinar also serves as an educational platform for learning more about the process of reformulating drugs as nasal products. It introduces nasal spray technology and nasal drug delivery systems, highlighting the expertise offered by Aptar Pharma in this domain. The company’s capabilities in accelerating the formulation process, whether for powder or liquid drugs, are discussed. This is particularly relevant for pharmaceutical companies looking to transition mature drug products to nasal delivery forms.

Case studies are presented to illustrate the practical applications and successes of drug repositioning via nasal reformulation. These examples provide insights into the tangible outcomes that can be achieved through this strategy. They serve as a testament to the potential of nasal drug delivery in extending the life and enhancing the utility of existing pharmaceutical products.

The webinar also highlights Aptarr Pharma’s role in assisting companies at various stages of drug development, specifically in the context of reformulating for nasal delivery. The company’s role in breathing new life into mature drug products is emphasized, showcasing its ability to guide and support pharmaceutical companies through the intricate process of drug repositioning.